Royal Society Publishing

The virtual physiological human: integrative approaches to computational biomedicine

Computational biomedicine is the use of computer-based tools and approaches to simulate and model the human body in health and disease. In Europe, this new science has become synonymous with the concept of the virtual physiological human (VPH). This initiative, set up in 2007, aims to develop an integrative framework of methods and technologies to investigate the human body as a whole, set to transform the study and practice of healthcare over the coming decades. The papers in this special issue of Interface Focus are a selection of those presented at VPH 2012, the second of two successful conferences supported by the VPH Network of Excellence, held in London from 18–20 September 2012 with 250 participants from many countries. A wide variety of papers on multi-scale modelling were presented at VPH 2012, representing a significantly wider range of organs and systems than that presented at the first VPH meeting two years earlier, which focussed heavily on the cardiovascular system. Complete sessions at the 2012 conference were devoted to modelling the respiratory system, the immune system, the musco-skeletal system and the central nervous system. A collection of abstracts from the first VPH conference, held in Brussels on 30 Sept – 1 Oct 2010, were also translated into an issue of Interface Focus, the papers from which can be viewed here.

Learn more about the virtual physiological human and computational biomedicine in our interview with two of the guest editors below.

Read all the articles from this issue online

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An interview with two of the organisers, Peter Coveney and Peter Hunter. 



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